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Corrections & amendments Author Correction: Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells

Sarah Tessier , Omar Ferhi , Marie-Claude Geoffroy , Román González-Prieto , Antoine Canat , et al.
Nature Communications, 2023, 14 (123), pp.1. ⟨10.1038/s41467-022-35750-z⟩
Article dans une revue hal-04053888v1

Abstract 803: Bromodomain and extra-terminal BET inhibitors induce TP53 independent apoptosis, maturation and oncoprotein degradation in NPM1 mutated acute myeloid leukemia

Thorsten Braun , Marie-Magdelaine Coudé , Jeannig Berrou , Hanene Djamai , Mélanie Dupont , et al.
Cancer Research, 2018, 78 (13_Supplement), pp.803-803. ⟨10.1158/1538-7445.AM2018-803⟩
Article dans une revue hal-04055422v1

Clonal Hematopoiesis Driven By MDM4 Amplification Defines a Canonical Route Towards Secondary MDS/AML in Fanconi Anemia Patients

Marie Sebert , Stéphanie Gachet , Thierry Leblanc , Alix Rousseau , Olivier Bluteau , et al.
Blood, 2021, 138 (Supplement 1), pp.860-860. ⟨10.1182/blood-2021-147811⟩
Article dans une revue hal-04054269v1
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Biological Effects of BET Inhibition by OTX015 (MK-8628) and JQ1 in NPM1-Mutated (NPM1c) Acute Myeloid Leukemia (AML)

Hanane Djamai , Jeannig Berrou , Mélanie Dupont , Marie-Magdelaine Coudé , Marc Delord , et al.
Biomedicines, 2021, 9, ⟨10.3390/biomedicines9111704⟩
Article dans une revue hal-04054282v1

Resistance to therapy in acute promyelocytic leukemia

J. Lehmann-Che , C. Bally , Hugues de Thé
New England Journal of Medicine, 2014, 371 (12), pp.1170-2. ⟨10.1056/NEJMc1409040⟩
Article dans une revue hal-03653838v1

The DNA binding property of PML/RARA but not the integrity of PML nuclear bodies is indispensable for leukemic transformation

X. Liu , H. Yuan , L. Peres , S. Chen , Z. Chen , et al.
PLoS ONE, 2014, 9 (8), pp.e104906. ⟨10.1371/journal.pone.0104906⟩
Article dans une revue hal-03653841v1

The HDAC inhibitor SAHA regulates CBX2 stability via a SUMO-triggered ubiquitin-mediated pathway in leukemia

Antonella Di Costanzo , Nunzio del Gaudio , Lidio Conte , Carmela Dell’aversana , Michiel Vermeulen , et al.
Oncogene, 2018, 37 (19), pp.2559-2572. ⟨10.1038/s41388-018-0143-1⟩
Article dans une revue hal-03653845v1

ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation

Zeina Dassouki , Umut Sahin , Hiba El Hajj , Florence Jollivet , Youmna Kfoury , et al.
Blood, 2015, 125 (3), pp.474-482. ⟨10.1182/blood-2014-04-572750⟩
Article dans une revue hal-03653847v1

HDAC inhibition does not induce estrogen receptor in human triple-negative breast cancer cell lines and patient-derived xenografts

Patricia De Cremoux , Mathieu Dalvai , Olivia N'Doye , Fatima Moutahir , Gaëlle Rolland , et al.
Breast Cancer Research and Treatment, 2015, 149 (1), pp.81-89. ⟨10.1007/s10549-014-3233-y⟩
Article dans une revue hal-03653860v1

Interferon controls SUMO availability via the Lin28 and let-7 axis to impede virus replication

Umut Sahin , Omar Ferhi , Xavier Carnec , Alessia Zamborlini , Laurent Peres , et al.
Nature Communications, 2014, 5, pp.4187. ⟨10.1038/ncomms5187⟩
Article dans une revue inserm-02440658v1

PML is a ROS sensor activating p53 upon oxidative stress

Michiko Niwa-Kawakita , Omar Ferhi , Hassane Soilihi , Morgane Le Bras , Valérie Lallemand-Breitenbach , et al.
Journal of Experimental Medicine, 2017, 214 (11), pp.3197-3206. ⟨10.1084/jem.20160301⟩
Article dans une revue hal-02348554v1

Acute promyelocytic leukemia, arsenic, and PML bodies

Hugues de Thé , Morgane Le Bras , Valérie Lallemand-Breitenbach
Journal of Cell Biology, 2012, 198 (1), pp.11-21. ⟨10.1083/jcb.201112044⟩
Article dans une revue hal-02442053v1

Curing APL through PML/RARA degradation by As2O3

Valérie Lallemand-Breitenbach , Jun Zhu , Zhu Chen , Hugues de Thé
Trends in Molecular Medicine, 2012, 18 (1), pp.36-42. ⟨10.1016/j.molmed.2011.10.001⟩
Article dans une revue hal-02442056v1

PML nuclear bodies: from architecture to function

Valérie Lallemand-Breitenbach , Hugues de Thé
Current Opinion in Cell Biology, 2018, 52, pp.154-161. ⟨10.1016/j.ceb.2018.03.011⟩
Article dans une revue hal-02441939v1

In APL, noncoding mutations and SNP converge on WT1

Hsin-Chieh Wu , Hugues de Thé
Blood, 2022, 140 (10), pp.1060-1061. ⟨10.1182/blood.2022017214⟩
Article dans une revue hal-04053930v1

GATA5 SUMOylation is indispensable for zebrafish cardiac development

Bin Wen , Hao Yuan , Xiaohui Liu , Haihong Wang , Saijuan Chen , et al.
Biochimica et Biophysica Acta (BBA) - General Subjects, 2017, 1861, pp.1691 - 1701. ⟨10.1016/j.bbagen.2017.03.005⟩
Article dans une revue hal-04055430v1
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The combination of arsenic, interferon-alpha, and zidovudine restores an "immunocompetent-like" micro-environment in patients with adult T-cell leukemia lymphoma

Ghada Kchour , Sa Rahim Rezaee , Reza Farid , Akram Ghantous , Houshang Rafatpana , et al.
Retrovirology, 2014, 11 (Suppl 1), pp.O4
Article dans une revue inserm-00924965v1

The acute promyelocytic leukaemia success story : curing leukaemia through targeted therapies

K. L. Rice , Hugues de Thé
Journal of Internal Medicine, 2014, 276 (1), pp.61-70. ⟨10.1111/joim.12208⟩
Article dans une revue hal-03653836v1

Long-term survival of advanced triple-negative breast cancers with a dose-intense cyclophosphamide/anthracycline neoadjuvant regimen

S. Giacchetti , R. Porcher , J. Lehmann-Che , A. S. Hamy , A. De Roquancourt , et al.
British journal of cancer, 2014, 110 (6), pp.1413-9. ⟨10.1038/bjc.2014.81⟩
Article dans une revue hal-03653840v1

Oncologie cellulaire et moléculaire

Hugues de Thé
L’annuaire du Collège de France : 2015-2016 : Cours et travaux, 2018, 116, pp.163-168. ⟨10.4000/annuaire-cdf.12819⟩
Article dans une revue hal-03653846v1

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells

Hiba El Hajj , Zeina Dassouki , Caroline Berthier , Emmanuel Raffoux , Lionel Ades , et al.
Blood, 2015, 125 (22), pp.3447-3454. ⟨10.1182/blood-2014-11-612416⟩
Article dans une revue hal-03653849v1

Functional TP53 mutations have no impact on response to cytotoxic agents in metastatic colon cancer

Jeanne Netter , Jacqueline Lehmann-Che , Jerome Lambert , Anne Tallet , Nelson Lourenco , et al.
Bulletin du Cancer, 2015, 102 (2), pp.117-125. ⟨10.1016/j.bulcan.2014.12.010⟩
Article dans une revue hal-03653852v1

Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy

Hsin-Chieh Wu , Domitille Rérolle , Caroline Berthier , Rita Hleihel , Takashi Sakamoto , et al.
Cancer Discovery, 2021, 11 (12), pp.3198-3213. ⟨10.1158/2159-8290.CD-21-0177⟩
Article dans une revue hal-03824271v1
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PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers

Géraldine Gentric , Yann Kieffer , Virginie Mieulet , Oumou Goundiam , Claire Bonneau , et al.
Cell Metabolism, 2019, 29 (1), pp.156-173.e10. ⟨10.1016/j.cmet.2018.09.002⟩
Article dans une revue inserm-02437801v1

Promyelocytic Leukemia Protein, a Protein at the Crossroad of Oxidative Stress and Metabolism

Sarah Tessier , Natalia Martin-Martin , Hugues de Thé , Arkaitz Carracedo , Valérie Lallemand-Breitenbach
Antioxidants and Redox Signaling, 2017, 26 (9), pp.432-444. ⟨10.1089/ars.2016.6898⟩
Article dans une revue hal-02441961v1
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Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish

Shuo Gao , Zixuan Wang , Luxiang Wang , Haihong Wang , Hao Yuan , et al.
PLoS Genetics, 2021, 17 (8), pp.e1009693. ⟨10.1371/journal.pgen.1009693⟩
Article dans une revue hal-04054293v1

TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy

Rui Meng Yang , Jiong Tao , Ming Zhan , Hao Yuan , Hai Hong Wang , et al.
Cell Death and Differentiation, 2019, 26 (11), pp.2430-2446. ⟨10.1038/s41418-019-0311-z⟩
Article dans une revue hal-02350278v1

TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers

B. Gyorffy , G. Bottai , J. Lehmann-Che , G. Keri , L. Orfi , et al.
Molecular oncology, 2014, 8 (3), pp.508-19. ⟨10.1016/j.molonc.2013.12.018⟩
Article dans une revue hal-03653831v1

Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine

C. Bally , L. Ades , A. Renneville , M. Sebert , V. Eclache , et al.
LEUKEMIA RESEARCH, 2014, 38 (7), pp.751-5. ⟨10.1016/j.leukres.2014.03.012⟩
Article dans une revue hal-03653835v1

Activation of a promyelocytic leukemia-tumor protein 53 axis underlies acute promyelocytic leukemia cure

J. Ablain , K. Rice , H. Soilihi , A. De Reynies , S. Minucci , et al.
Nature Medicine, 2014, 20 (2), pp.167-174. ⟨10.1038/nm.3441⟩
Article dans une revue hal-03653839v1